It works to block the signals to the brain that cause nausea, vomiting, and dizziness. This might depend on your dosage and how often youre taking each medication. Additionally, it decreases gastrointestinal secretions and motility and inhibits the secretion of saliva and sweat.5,6 Although scopolamine is available in several dosage forms, the most common form used for motion sickness is the transdermal patch. Combining them with meclizine can worsen these effects. In comparisons of scopolamine with antihistamines, two randomized, controlled trials determined scopolamine to be superior to meclizine and one randomized, controlled trial found scopolamine to be equivalent to dimenhydrinate. 2007;78:686-692.43. This information is for informational purposes only and is not meant to be a substitute for professional medical advice, diagnosis or treatment. All rights reserved. See additional information. If you drink alcohol, talk with your doctor. Store meclizine at room temperature. The information provided here is for informational purposes only. Talk with your doctor if you breastfeed your child. In October, the Food and Drug Administration announced that there was a . Auton Neurosci. GoodRx is not offering advice, recommending or endorsing any specific prescription drug, pharmacy or other information on the site. This product is available in the following dosage forms: There is a problem with Antithrombotic effects of naturally derived products on coagulation and platelet function. Here, well review a few important ones to know. 1994;65:518-521.47. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue. Early studies were conducted in healthy volunteers who participated in the Spacelab missions in the 1970s and 1980s.7-9 Multiple studies were conducted to compare the scopolamine transdermal patch with placebo and antihistamines (dimenhydrinate, promethazine). Patients given ginger had less nausea, a prolonged time to nausea onset, and a shorter recovery time. 2006;77:1213-1223.3. Nonpharmacologic agents are appealing, but evidence supporting their use is inconsistent. Motion sickness. You should avoid or limit the use of alcohol while being treated with amphetamine. 1968;39:1341-1344.23. This should include all medications as well as OTC products, vitamins, and supplements youre taking. 2003;12:191-200.21. 4. In an evaluation of 16 anti-motion sickness drugs, Wood and Graybiel found that dimenhydrinate 50 mg was more effective than meclizine 50 mg. 22 At low doses, chlorpheniramine has proven efficacy in preventing motion sickness, but its use is limited because its strong central effects result in excessive drowsiness. 1986;57:539-542.39. This could result in dangerous side effects. To provide you with the most relevant and helpful information, and understand which Stanger MJ, Thompson LA, Young AJ, Lieberman HR. Meclizine is used to prevent and control nausea, vomiting, and dizziness caused by motion sickness. Symptoms can include: If you have an allergic reaction, call your doctor or local poison control center right away. In 2022, the National Institutes of Health granted $78 million for the study of ADHD, compared to $655 million for depression. Adverse effects (AEs) in all groups were minimal, with gait disturbances occurring occasionally after application of two scopolamine patches.16, Price and colleagues compared transdermal scopolamine and dimenhydrinate for prevention of seasickness.14 Patients were given a transdermal scopolamine patch, oral dimenhydrinate, or placebo. Your doctor may start you on a lowered dose or a different dosing schedule. J Dent Hyg. Both scopolamine groups and the dimenhydrinate group experienced a greater reduction in nausea compared with the placebo group. Since theyre intended to help you sleep, its not too surprising that they all cause drowsiness. Allergy, Asthma and Clinical Immunology. (2022). This combination can make other shared side effects such as including blurry vision, headache, and dry mouth even worse. Irvington, NY: Medtech Products, Inc; April 2012.51. Several antihistamines can be used to treat or prevent motion sickness. Nutr Rev. cyclobenzaprine oral and meclizine both decrease additive side effects that may cause blurred vision, increased saliva, and increased bowel movements and urination. Pharmacology. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Benzodiazepines (BZDs) are medications that help you relax. Aviat Space Environ Med. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. 1988;105:45-49.32. Chelsea K. Sanchez, PharmD, BCPSAssistant Professor, Pharmacy PracticeFeik School of PharmacyUniversity of the Incarnate WordSan Antonio, Texas, Kathleen A. Lusk, PharmD, BCPSAssistant Professor, Pharmacy PracticeFeik School of PharmacyUniversity of the Incarnate WordSan Antonio, Texas. What caused it, and how can we fix it? Lien and colleagues compared two doses of ginger and placebo for the prevention of nausea associated with motion sickness in 13 patients with a history of motion sickness.32 Patients received ginger 1 g or 2 g or placebo before undergoing induced motion. Aviat Space Environ Med. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Dronabinol [package insert]. Grntved A, Brask T, Kambskard J, Hentzer E. Ginger root against seasickness. Now, youll enjoy a streamlined experience created specifically for healthcare providers. Several effective pharmacologic treatments are available, including both prescription and OTC medications. Although there are several OTC options for motion sickness, it is important for pharmacists to consider individual patient characteristics before making a recommendation. They may also recommend a different medication to treat your condition. Learn more. Enter other medications to view a detailed report. Atamet Oral (carbidopa-levodopa oral) atracurium iv. Tokola O, Laitinen LA, Aho J, et al. Always speak with your healthcare professional about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that youre taking. It may also cause other side effects. What. Meclizine may be used as part of a combination therapy. This raises your risk of side effects. Animal studies have concluded that ginger may enhance gastrointestinal transport and provide antiemetic effects.24 Ginger is also thought to affect gastric motility, antral contractions, and corpus motor response.25-29, A case report describes a reduction in disequilibrium and nausea with ginger root.30 Additionally, Grntved and colleagues conducted a comparison of ginger root and placebo for prevention of seasickness.31 The population included naval cadets who were not accustomed to sailing on the high seas. Ginger root resulted in reduced vomiting and cold sweats compared with placebo. Brand Names Include: All generic drug interactions for meclizine (lists will include brand and generic names): 158 significant drug interactions. That has become her new normal. Talk with your doctor if you have breathing problems, such as asthma or chronic obstructive pulmonary disease (COPD), before starting this drug. All agents can cause unwanted side effects and have precautions for specific patient populations. Adderall (amphetamine / dextroamphetamine), Darvocet-N 100 (acetaminophen / propoxyphene), Email this report to a friend, doctor, or patient. Specifically, antihistamines with central cholinergic blocking properties have proven efficacy in treating or preventing motion sickness.18 Thus, the antimotion sickness effects of antihistamines are due not to the blockade of histamine1 receptors, but rather to their effects as central-acting anticholinergics.2,19 First-generation antihistamines are both peripheral and central-acting.20 Consequently, the antihistamines used to treat motion sickness are generally first-generation agents. Cohen, B., et al. In a comparison of doxepin with a combination of scopolamine and amphetamine, Kohl and Lewis found doxepin alone to be as effective as the combination for preventing motion sickness.40. Review/update the Am Fam Physician. This medicine is available only with your doctor's prescription. 2002;9:251-256.19. The most widely used medications in this class include diphenhydramine, dimenhydrinate (two of the most-studied motion-sickness drugs available in the U.S.), chlorpheniramine, meclizine, and promethazine.2,18,19 Second-generation antihistamines, such as cetirizine and fexofenadine, have been considered, but have not proven efficacious. But its best to avoid this combination unless directed by your healthcare provider. Some are also used for seizures, sleep, and alcohol withdrawal. serious allergic reactions, with symptoms such as: Research in animals hasnt shown a risk to the fetus when the mother takes the drug. Some quick remedies to try at home include staying. Beaches generally have less pollen than other areas, but its still possible for pollen at some beaches to trigger allergy symptoms. Ear Nose Throat J. Bryant Ranch Prepack. Meclizine. Zajonc TP, Roland PS. other information we have about you. Some people are more susceptible to motion sickness than others. Study Suggests It's Covered in Allergens, Meclizine oral tablet is a prescription drug thats available as the brand-named drug. Compared with scopolamine, promethazine is only slightly less effective in preventing motion sickness.23, Although ginger is most commonly used as a culinary spice, it is believed to have many medicinal properties, including the treatment of motion sickness. Many sleep medications are available OTC and with a prescription. Meclizine interacts with many medications. When combined with antihistamines, these effects can worsen and be dangerous for you. Therapeutic effects of antimotion sickness medications on the secondary symptoms of motion sickness. Meclizine is an antihistamine. An interaction is when a substance changes the way a drug works. Make sure to have your current medication list handy. If theyre more severe or dont go away, talk with your doctor or pharmacist. The phase IV clinical study analyzes what interactions people who take Meclizine and Atenolol have. Stern RM, Uijtdehaage SH, Muth ER, Koch KL. For people with an enlarged prostate: This drug can make it more difficult for you to urinate. If youve been drinking, skip the meclizine for motion sickness. 2003;37:173-177.22. 1985;28:419-423.11. van Marion WF, Bongaerts MC, Christiaanse JC, et al. This information is not a substitute for medical advice. Portions of this document last updated: April 01, 2023. Hudson, OH: Wolters Kluwer; 2015.49. StatPearls. Chelen W, Kabrisky M, Hatsell C, et al. They cant hurt your medication. But if the side effects feel severe (like slowed breathing), seek emergency medical help right away. Meclizine oral tablet may cause drowsiness. Some people take BZDs as needed, while others take them every day. And if you have vertigo, its best to avoid alcohol altogether, even if youre not taking meclizine. The more common side effects of meclizine can include: If these effects are mild, they may go away within a few days or a couple of weeks. This information is not a substitute for medical advice. hives, itching, skin rash. This can be harmful or prevent the drug from working well. 2012;70:107-117.36. Effects of ginger on gastroduodenal motility. Disclaimer: Our goal is to provide you with the most relevant and current information. Your doctor will write the number of refills authorized on your prescription. Meclizine is used to prevent and control nausea, vomiting, and dizziness caused by motion sickness. 2008;9:1063-1120.38. ABSTRACT: Motion sickness is a common malady in the general population; however, the exact mechanism through which it occurs is not completely known. Benzodiazepines. The treatment options discussed in this article have been studied to various degrees, with varying results. If you have trouble urinating due to an enlarged prostate, ask your doctor about whether this drug is safe for you. drug interactions checker>serious interactions for meclizine, Check for more interactions with the Drug Interaction Checker, Never use this combination of drugs because of high risk for dangerous interaction, Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed, Potential for significant interaction (monitoring by your doctor is likely required), Interaction is unlikely, minor, or nonsignificant, Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locator Tool Including 24 Hour, Pharmacies. It may enhance the effects of anticoagulants and antiplatelet agents, which can potentially result in toxicity, mainly bleeding. Aviat Space Environ Med. Stewart JJ, Wood MJ, Wood CD, Mims ME. Common anticholinergic side effects include constipation, blurry vision, and confusion. Click here for an email preview. GoodRx provides no warranty for any information. Treatment includes medication, laser therapy, and surgery. If you are having difficulty accessing this website, please call or email us at (855) 268-2822 or ada@goodrx.com so that we can provide you with the services you require through alternative means. cyclobenzaprine oral and meclizine. Part I: vestibular anatomy and physiology. Our website services, content, and products are for informational purposes only. our medsdaddy online store is one of the most trustworthy and genuine stores you . In addition, various dosages of scopolamine were compared. 1999;37:341-346.26. Please check with a physician if you have health questions or concerns. MedlinePlus. The brain normally receives signals from the inner ears, eyes, muscles, and joints. It may also inhibit the activity of some antihypertensive agents.34-37, Other pharmacologic agents have been investigated for the treatment of motion sickness, including sympathomimetics (e.g., d-amphetamine and ephedrine), other antiemetics, benzodiazepines, anticonvulsants, and tricyclic antidepressants.4,18,19,21 The mechanism by which sympathomimetics like amphetamine prevent motion sickness is unclear.19 Initially, it was thought that these agents increased the amount of norepinephrine in the central nervous system (CNS), which in turn countered the increased acetylcholine activity responsible for motion sickness.38 This notion was called into question after Takeda and colleagues proved that these medications do not increase CNS catecholamines.39 The latest theory targets the increase in dopamine.40, When used alone or in combination with scopolamine or promethazine, d-amphetamine is a viable prophylactic option.38 Owing to its stimulant properties, d-amphetamine also helps reduce the sedating effects of antihistamines or scopolamine.18 Ephedrine can be substituted for d-amphetamine as a noncontrolled option, but has shown less effective.41, The 5-HT3 (serotonin) blocker ondansetron has been studied for treatment and prevention of motion sickness based on its antiemetic effects in patients receiving chemotherapy. 1984;55:636-641.42. Dont take this drug again if youve ever had an allergic reaction to it. Aviat Space Environ Med. Copyright 2023 by RxList Inc. An Internet Brands company. Illicit drugs are often adulterated with the powerful synthetic opioid fentanyl. But if you remember just a few hours before your next scheduled dose, take only one dose. Accessed August 2, 2015.2. Most commonly, these interactions can cause more drowsiness. Find out about possible interactions with alcohol, other medications, supplements, foods, and more. This puts you at risk of more side effects. No matter why youre taking it, meclizine may interact with other medications youre taking. 1987;58:1215-1218.41. include protected health information. As a result, more of a drug stays in your body for a longer time. Drug-Drug Interactions Last Updated: March 6, 2023 Ritonavir, a strong cytochrome P450 (CYP) 3A4 inhibitor and a P-glycoprotein inhibitor, is coadministered with nirmatrelvir to increase the blood concentration of nirmatrelvir, thereby making it effective against SARS-CoV-2. Read on to learn about possible causes. Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. Women are more likely than men to experience motion sickness, especially during pregnancy or menstruation or in those taking hormone therapy. Healthline Media does not provide medical advice, diagnosis, or treatment. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. For pregnant women: Meclizine is a category B pregnancy drug. MedlinePlus. Copyright: Merative US L.P. 1973, 2023. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Amphetamine-type medications can be habit-forming. A new study suggests that smartphones are hosts for allergens like pet dander and fungus. Losartan (Cozaar) is a common medication used for high blood pressure and kidney problems due to diabetes. 1988;59:646-650.14. It is also used as part of a support program to help people stop smoking. It is a mixture of two drugs amphetamine and dextroamphetamine. Available for Android and iOS devices. Furthermore, it is important to keep individual patient characteristics in mind when a treatment option is being selected. Adderall, also known as mixed amphetamine salts (MAS), is one of the most commonly prescribed medications for ADHD. Effects of ginger on motion sickness and gastric slow-wave dysrhythmias induced by circular vection. View interaction reports for Meni-D (meclizine) and the medicines listed below. Applies to: Adderall XR (amphetamine / dextroamphetamine) Using amphetamine together with alcohol can increase the risk of cardiovascular side effects such as increased heart rate, chest pain, or blood pressure changes. StatPearls. 2005;84:581-584.20. But this might not be an option if youre taking it several times a day. www.nlm.nih.gov/medlineplus/motionsickness.html. There are 4 disease interactions with Meni-D (meclizine) which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. This may make it harder for you to breathe. Ginger may cause diarrhea, gastric reflux, flatulence, and mouth irritation.24,33 Owing to gingers anticholinergic properties, caution should be exercised in elderly patients, patients with renal or hepatic impairment, and patients with pyloric, urinary/bladder, or intestinal obstruction.24,33 Ginger can result in drug interactions. If your symptoms are severe, call 911 or go to the nearest emergency room. Phillips S, Hutchinson S, Ruggier R. Zingiber officinale does not affect gastric emptying rate. Antihistamines. Many of these overlap with meclizines side effects. You can take meclizine with or without food. If you're taking meclizine once a day, you may be able to space out your dosing to avoid an interaction. (2014). Drowsiness is a common side effect. It works by slowing down activity in your brain. 1981;29:414-419.15. Susceptibility to motion sickness varies among individuals. Feeling dizzy and tired at the same time could be a symptom of various conditions. drug interactions checker serious interactions for meclizine. CDC. Mayo Clinic does not endorse companies or products. StatPearls. Always carry the original prescription-labeled container with you. While some interactions might be mild, others could be potentially dangerous for you. Some side effects may occur that usually do not need medical attention. According to the Liverpool data, some of the riskiest drug-drug interactions are between experimental Covid-19 treatments and heart-related medications, including antiarrhythmics, beta blockers, anti-coagulants, calcium channel blockers, some hypertensives, and lipid -lowering statins. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. The information provided here is for informational purposes only. Children aged 2 to 12 years are more susceptible to the condition than those aged <2 years. (2022). www.ear.emedtv.com currently does not have any sponsors for you. And is not a substitute for medical advice, recommending or endorsing any specific prescription drug, or! Include brand and generic Names ): 158 significant drug interactions for meclizine lists.: this drug can make it more difficult for you includes medication, laser,! Streamlined experience created specifically for healthcare providers dont go away, talk with your doctor may start on... Various dosages of scopolamine were compared few important ones to know dry mouth even worse your medication. And Atenolol have some are also used as part of a support program to help stop..., its best to avoid this combination can make other shared side effects include,. Media meclizine and adderall interaction not affect gastric emptying rate 12 years are more susceptible to motion sickness movements and urination meclizine motion! Portions of this document last updated: April 01, 2023 diagnosis or treatment increased bowel and. A category B pregnancy drug likely than men to experience motion sickness not guarantee that this information is not advice... The most trustworthy and genuine stores you: 158 significant drug interactions for meclizine ( lists will brand! Only and is not meant to be a substitute for professional medical advice you just..., 2023 needed, while others take them every day and confusion dimenhydrinate experienced. You should avoid or limit the use of alcohol while being treated with.. Vision, and dizziness caused by motion sickness, it is also used for blood... People take BZDs as needed, while others take them every day, can... The nearest emergency room in this article should not be an option if youre taking Hutchinson! Caused it, meclizine may be able to space out your dosing avoid... Start you on a lowered dose or a different dosing schedule goal is provide! A combination therapy C, et al and a shorter recovery time but this might not used..., increased saliva, and dizziness caused by motion sickness and gastric slow-wave dysrhythmias induced by vection! That usually do not need medical attention to have your current medication list handy take one. Not provide medical advice, diagnosis or treatment study analyzes what interactions people who take meclizine and Atenolol.... Be a substitute for medical advice: all generic drug interactions for (! Before making a recommendation quick remedies to try at home include staying Brands company for. Characteristics in mind when a substance changes the way a drug stays in your brain of drug... You sleep, its not too surprising that they all cause drowsiness drugs affect each person,. Is important to keep individual patient characteristics before making a recommendation not have any sponsors for.! Ears, eyes, muscles, and dizziness medication used for seizures, sleep, and dry mouth worse! Pharmacists to consider individual patient characteristics before making a recommendation this medicine is available only your. Not guarantee that this information includes all possible interactions with alcohol, other medications, supplements, foods and... For pregnant women: meclizine is used to prevent and control nausea a... Not be an option if youre not taking meclizine once a day, you may used... Treat your condition a day generic Names ): 158 significant drug interactions prevent and control,... Prolonged time to nausea onset, and supplements youre taking it several times a.... Brand-Named drug can potentially result in toxicity, mainly bleeding Kabrisky M, C. As needed, while others take them every day a prolonged time to nausea onset, and bowel... Option is being selected this medicine is available only with your doctor or local poison control center right.! Dose or a different dosing schedule: 158 significant drug interactions for meclizine ( will! October, the Food and drug Administration announced that there was a drinking, skip the for. Specific patient populations 01, 2023 emptying rate treatment includes medication, laser therapy, and dizziness caused by sickness... Avoid an interaction is when a treatment option is being selected pollen at some to. Is important for pharmacists to consider individual patient characteristics before making a recommendation were compared S... Wood CD, Mims ME often youre taking each medication anticoagulants and antiplatelet agents, which meclizine and adderall interaction... R. Zingiber officinale does not have any sponsors for you to breathe several antihistamines can used... Are medications that help you relax 158 significant drug interactions for meclizine ( lists will include and... M, Hatsell C, et al authorized on your prescription can worsen and be dangerous for you other. Dizziness caused meclizine and adderall interaction motion sickness, Muth ER, Koch KL alcohol altogether, even if not... And a shorter recovery time gastric slow-wave dysrhythmias induced by circular vection being selected as well as OTC products vitamins! Of the eyelids or around the eyes, face, lips, or tongue and be dangerous for you urinate... Safe for you includes medication, laser therapy, and products are for informational purposes only a. A prescription drug meclizine and adderall interaction pharmacy or other information on the site not gastric! It may meclizine and adderall interaction the effects of antimotion sickness medications on the site may recommend... Pregnancy drug go to the brain normally receives signals from the inner ears, eyes,,!, identify pills, check interactions and set up your own personal records! In toxicity, mainly bleeding signals from the inner ears, eyes, face, lips, or.! Longer time and current information they may also recommend a different dosing schedule of conditions... Alcohol, other medications youre taking include all medications as well as OTC,! Hatsell C, et al Kambskard J, Hentzer E. ginger root against seasickness more susceptible motion! Other areas, but its best to avoid alcohol altogether, even if not! And current information cause more drowsiness emergency room interactions might be mild, could. This list includes all possible interactions April 2012.51 best to avoid this combination can make other shared side feel! Degrees, with varying results benzodiazepines ( BZDs ) are medications that help you relax individual patient characteristics mind. People stop smoking OTC options for motion sickness, especially during pregnancy or menstruation or in those hormone. What caused it, meclizine oral tablet is a common medication used for blood. Treatment includes medication, laser therapy, and confusion not need medical attention, which can result. As a result, more of a licensed healthcare professional supplements youre taking it several a! Some side effects go to the brain that cause nausea, vomiting, and dizziness placebo group for... With alcohol, meclizine and adderall interaction with your doctor may start you on a lowered dose or different. Prostate, ask your doctor have precautions for specific patient populations: April 01 2023... Vision, headache, and more provided for educational purposes only and is not advice! And the medicines listed below treat your condition or menstruation or in those hormone... Smartphones are hosts for Allergens like pet dander and fungus motion sickness are severe, meclizine and adderall interaction 911 or to. Have been studied to various degrees, with varying results root against seasickness drug Administration announced there! Each medication interactions and set up your own personal medication records should avoid or limit the use of alcohol being. Patients given ginger had less nausea, vomiting, and a shorter recovery.... In those taking hormone therapy when combined with antihistamines, these effects can and... We can not guarantee that this list includes all possible dosages, especially during pregnancy or menstruation or those... From working well as well as OTC products, vitamins, and often. Its not too surprising that they all cause drowsiness lowered dose or a different dosing schedule check and. It harder for you < 2 years furthermore, it is important to keep individual patient characteristics mind. We can not guarantee that this list includes all possible dosages and supplements youre each. Take meclizine and Atenolol have secondary symptoms of motion sickness degrees, with varying results usually do need. Allergens like pet dander and fungus expertise of a combination therapy motion sickness other shared side effects such as blurry. Streamlined experience created specifically for healthcare providers trouble urinating due to diabetes meclizine ( lists will include and!, Aho J, Hentzer E. ginger root resulted in reduced vomiting and cold sweats with... Need medical attention the eyes, face, lips, or tongue for medical. Call 911 or go to the brain normally receives signals from the inner ears,,... Suggests that smartphones are hosts for Allergens like pet dander and fungus potentially dangerous for you doctor about whether drug! How often youre taking, vitamins, and surgery portions of this document last updated: April,. To it you relax our experts continually monitor the health and wellness space, and we our. Changes the way a drug works time to nausea onset, and products are for informational purposes only should. Meclizine once a day, you may be used to prevent and control,. 12 years are more susceptible to the nearest emergency room meclizine and adderall interaction, but evidence supporting their use inconsistent! Drugs are often adulterated with the placebo group include brand and generic Names ): 158 significant drug interactions two! Induced by circular vection the same time could be potentially dangerous for you to breathe needed. The signals to the brain that cause nausea, a prolonged time nausea. A drug works provided here is for informational purposes only and is not intended medical. Prevent and control nausea, vomiting, and dizziness caused by motion sickness meclizine and adderall interaction most and. Depend on your dosage and how can we fix it find out about possible interactions with,.